2024 NIPS NeurIPS 2024

Equivariant Neural Diffusion for Molecule Generation

Abstract

We introduce Equivariant Neural Diffusion (END), a novel diffusion model for molecule generation in 3D that is equivariant to Euclidean transformations. Compared to current state-of-the-art equivariant diffusion models, the key innovation in END lies in its learnable forward process for enhanced generative modelling. Rather than pre-specified, the forward process is parameterized through a time- and data-dependent transformation that is equivariant to rigid transformations. Through a series of experiments on standard molecule generation benchmarks, we demonstrate the competitive performance of END compared to several strong baselines for both unconditional and conditional generation.

🧭 Keyword Pioneer — equivariant diffusion
🐝 Cross-Pollinator — Artificial Intelligence, Computer Vision, Data Science & Analytics, Deep Learning, Healthcare & Medicine, Interdisciplinary, Knowledge & Reasoning, Machine Learning, Mathematics & Optimization, Natural Language Processing, Reinforcement Learning, Robotics, Speech & Audio
🌉 Interdisciplinary Bridge — Deep Learning and Interdisciplinary and Machine Learning