DiffECG: Diffusion Model-Powered Label-Efficient and Personalized Arrhythmia Diagnosis

Arrhythmia diagnosis using electrocardiogram (ECG) is critical for preventing cardiovascular risks. However, existing deep learning-based methods struggle with label scarcity and contrastive learning-based methods suffer from false-negative samples, which lead to poor model generalization. Besides, due to inter-subject variability, pre-trained models cannot achieve evenly performance across individuals. Conducting model fine-tuning for each individual is computationally expensive and does not guarantee improvement. We propose DiffECG, a diffusion-based self-supervised learning framework for label-efficient and personalized arrhythmia detection. Our method utilizes a diffusion model to extract robust ECG representations, coupled with a novel feature extractor and a multi-modal feature fusion strategy to obtain a well-generalized model. Moreover, we propose an efficient model personalization mechanism based on zeroth-order optimization. It personalizes the model by tuning the noise-adding step t in the diffusion process, significantly reducing computational costs compared to model fine-tuning. Experimental results show that our proposed method outperforms the SOTA method by 37.9% and 23.9% in generalization and personalization performance, respectively. The source code is available at: https://github.com/Auguuust/DiffEC