2008
NIPS
NeurIPS 2008
Efficient Inference in Phylogenetic InDel Trees
Abstract
Accurate and efficient inference in evolutionary trees is a central problem in computational biology. Realistic models require tracking insertions and deletions along the phylogenetic tree, making inference challenging. We propose new sampling techniques that speed up inference and improve the quality of the samples. We compare our method to previous approaches and show performance improvement on metrics evaluating multiple sequence alignment and reconstruction of ancestral sequences.
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Interdisciplinary Bridge
— Data Science & Analytics and Healthcare & Medicine and Machine Learning
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Keyword Pioneer
— sequence alignment
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Cross-Pollinator
— Artificial Intelligence, Computer Science, Computer Vision, Data Science & Analytics, Deep Learning, Healthcare & Medicine, Interdisciplinary, Knowledge & Reasoning, Machine Learning, Mathematics & Optimization, Natural Language Processing, Reinforcement Learning, Robotics, Security & Privacy, Speech & Audio
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Trend Setter
— Time Series
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Hot Topic Early Bird
— markov chain monte carlo
Authors
Topics
Keywords
bayesian inference
markov chain monte carlo
sequence alignment
ancestral sequences
evolutionary trees
insertions deletions
mcmc sampling
ancest序列 reconstruction
evolutionary biology
phylogenetic inference
phylogenetic tree
ancest sequence reconstruction
insertions and deletion
insertion deletion
ancestral sequence reconstruction